The protection and efficacy of combinations of VIAGRA with other PDE5 Inhibitors, which includes REVATIO or other pulmonary arterial hypertension (PAH) treatment options containing sildenafil, or other treatments for erectile dysfunction have not been analyzed.

In step with its recognised effects about the nitric oxide/cGMP pathway [see Medical PHARMACOLOGY], VIAGRA was revealed to potentiate the hypotensive consequences of nitrates, and its administration to clients who're utilizing nitric oxide donors such as natural nitrates or natural and organic nitrites in almost any variety either routinely and/or intermittently is consequently contraindicated.

On the other hand, there won't be any controlled medical knowledge on the security or efficacy of VIAGRA in sufferers with sickle mobile or associated anemias.

Dette kan spesielt være dersom tabletten tas med et stort eller fett måltid kan absorberingen av virkemiddelet forsinkes. Alkohol kan redusere effekten av potenspillen, og det anbefales derfor ikke at male tar medisinen i kombinasjon med overdrevne mengder alkohol.

Breastfeeding. Sildenafil passes into breast milk. Inform your healthcare service provider For anyone who is breastfeeding or intend to breastfeed. Your healthcare provider will advise you if you need to choose sildenafil when breastfeeding. 

Nosebleeds. Sildenafil could trigger nosebleeds. You could be at increased chance for this if you are taking a blood thinner medication. Notify your Health care company if you obtain nosebleeds typically when getting sildenafil. Should your nosebleed is critical or won't end after applying pressure, get help straight away. 

Most scientific studies assessed the efficacy of VIAGRA around 60 minutes put up dose. The erectile response, as assessed by RigiScan®, usually elevated with increasing sildenafil dose and plasma focus. Enough time course of impact was examined in one analyze, displaying an effect for as many as four hrs though the reaction was diminished in comparison to two hrs.

At solitary oral doses of 100 mg and 200 mg, transient dose-relevant impairment of color discrimination was detected utilizing the Farnsworth-Munsell 100-hue take a look at, with peak consequences near the time of peak plasma stages. This obtaining is per the inhibition of PDE6, that is involved in phototransduction within the retina.

In reports with healthier volunteers of one doses approximately 800 mg, adverse reactions were just like These found at reduce doses but incidence rates and severities had been amplified.

Snakk med lege før du tar legemidlet dersom du har høyt blodtrykk som ikke er godt behandlet eller uregelmessige hjerteslag/hjertebank. Les pakning og pakningsvedlegg nøye før bruk.

This document doesn't include all possible Unwanted side effects and Other people may perhaps arise. Examine using your physician For extra specifics of Unintended effects.

Analysis of the security databases from managed scientific get more info trials confirmed no apparent change in adverse reactions in patients having VIAGRA with and without the need of anti-hypertensive medication.

If you're taking sildenafil Once you consume a higher-Body fat food, for instance a burger and fries, it may well consider longer to start Operating.

Identical consequences on blood pressure level were being pointed out with twenty five mg, 50 mg and a hundred mg of VIAGRA, thus the effects are certainly not associated with dose or plasma ranges inside this dosage selection. Larger effects were being recorded among clients acquiring concomitant nitrates [see CONTRAINDICATIONS].